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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 15.45
Human Site: S1484 Identified Species: 28.33
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 S1484 P N L V A P T S Q S L I T P P
Chimpanzee Pan troglodytes XP_001138050 2188 240763 S1498 P N L V A P T S Q S L I T P P
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 S1484 P N L V A P T S Q S L I T P P
Dog Lupus familis XP_537704 2182 240593 S1492 P N L V A P A S Q S L I T S P
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 N1483 P N L V A P P N Q S L V T A P
Rat Rattus norvegicus NP_001100505 2040 223488 A1377 P S A T L A S A A S S T M T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 P1480 L S Q P N L I P P A S Q P V P
Chicken Gallus gallus XP_415884 2225 244861 S1535 T N L V P P S S Q P A S A L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 K1427 S E A L N K L K L Y A H V C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 D1926 H T P I R G W D G F L Q V G A
Honey Bee Apis mellifera XP_393643 1982 216109 L1319 A Q V C N H R L A P Y L T Q V
Nematode Worm Caenorhab. elegans Q93442 2862 325119 A2181 N E Q Y P P E A Q Q A P S P V
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 F464 C R A Y V A P F L N Q E Q P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 100 86.6 N.A. 73.3 13.3 N.A. 6.6 46.6 N.A. 0 N.A. 6.6 6.6 20 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 33.3 N.A. 20 53.3 N.A. 6.6 N.A. 13.3 20 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 24 0 39 16 8 16 16 8 24 0 8 8 8 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % D
% Glu: 0 16 0 0 0 0 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % G
% His: 8 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 0 31 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 0 47 8 8 8 8 8 16 0 47 8 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 47 0 0 24 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 47 0 8 8 16 54 16 8 8 16 0 8 8 39 54 % P
% Gln: 0 8 16 0 0 0 0 0 54 8 8 16 8 8 0 % Q
% Arg: 0 8 0 0 8 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 8 16 0 0 0 0 16 39 0 47 16 8 8 8 0 % S
% Thr: 8 8 0 8 0 0 24 0 0 0 0 8 47 8 0 % T
% Val: 0 0 8 47 8 0 0 0 0 0 0 8 16 8 16 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 16 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _